3PeteNC
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yea I thought about that, but when a person is shutdown from a dbol 6 weeker and another from a prop 12 weeker shouldn't it be somewhat the same, because both are producing the same amout of test, 0
It's still gonna depend on the user. Some people will "bounce back" faster than others.yea I thought about that, but when a person is shutdown from a dbol 6 weeker and another from a prop 12 weeker shouldn't it be somewhat the same, because both are producing the same amout of test, 0
Question: So what happens to your test levels when taking an AI, like Letro?Le Chatelier's Principle for the scientifically impaired:
Let's pretend A and B react to make C (can't get much simpler than that).
A + B --------> C
So we have a mixture containing A, B, and C. According to LeChatlier's principle, if we add more C to the mixture, the amounts of A and B will increase. If we remove some of the C from the mixture, A and B will decrease. And if we were to add A, B, or a combination of the two, C will increase. Still with me here? Good.
1) Yes. This pretty much effects all your steroid hormones. to varying degrees. 7-keto and metabolites have a slight anti-estrogenic effect.Okay a few questions on this:
1. If its a constant hormonal balance, what increases/decreases if you are using a cortisol reducer ON cycle? Estrogen? Test? Other hormones?
2. Is a cortisol reducer a bad idea ON cycle?
I'll start with those...
Testosterone + Aromatase = EstrogenQuestion: So what happens to your test levels when taking an AI, like Letro?
"Technically" zero is an asymptote, so your test levels will only approach zero.So if you are taking an exogenous form of test does your body immediately stop producing it naturally? So your natural test level is actually zero? Or would you still be producing some form of natural test?
I assume this is dependent on the time, dosage, etc? This is basically your level of shutdown correct?
"Technically" zero is an asymptote, so your test levels will only approach zero.
Your natural test levels decrease as the exogeneous levels begin taking its place in various biochemical reactions. Then we factor in a fun word called "reaction rate" and yeah, it's not always instantaneous. Shutdown is dependent on compound, dosage, and time.
You're throwin' out some tough Q's there Travis. I'll try my best to answer them, just remember that I'm not the guy with ALL the answers.
Oh, endocrinology interests the crap out of me as well. If it weren't for the fact that I'd have accelerated Pharm. students f*cking up the grading curves, I would have signed up for Biochemistry, but I'd rather have a nice GPA than get another chunk taken out from taking overlapping courses with them.You must spread some Reputation around before giving it to thesinner again.
Thanks bro. I guess endocrinology is pretty interesting to me. You seem to have a very good handle on it! Any suggestions on beginner reading material? I have a degree in economics so basically this stuff is all new.
If nothing else its nice to have these discussions. It's why I love coming to AM!
Cool. I'll pry check out some basic chemistry books on amazon. Should be able to find something I can understand.Oh, endocrinology interests the crap out of me as well. If it weren't for the fact that I'd have accelerated Pharm. students f*cking up the grading curves, I would have signed up for Biochemistry, but I'd rather have a nice GPA than get another chunk taken out from taking overlapping courses with them.
The concepts expressed in my original post, you could probably read about in any good general chemistry book. Of course, they would be applying it to much simpler chemical reactions. Le Chatelier's principle and chemical equilibria are concepts taught in Freshman Chemistry II, but are used in much more advanced chemistry.
Let's also start by saying that you don't have to run post cycle therapy.........you also don't have to wipe your ass after taking a dump: it's just a really really good idea to do these things :dump:
The first thing we need to understand is what is going on with our bodies when we're taking anabolic steroids:
Exogeneous anabolic hormones (or derivatives of anabolic hormones) are being brought into your system. This causes the body to take a number of responsive actions. The first and foremost (as you already know) is increased muscle mass. Unfortunately, other things are also going on that aren't so great
When an enzyme or hormone is brought exogeneously into the system, chemical balances shift around to attain a certain equilibrium. This is a chemical concept known as Le Chatelier's Principle of Chemical Equilibria. In a nutshell, your body will increase production of estrogen, cortisol, and other hormones in response to heightened testosterone levels, while simultaneously slowering (or completely stopping) natural production of testosterone. Biologist call this negative feedback.......biology sucks doesn't it?
Le Chatelier's Principle for the scientifically impaired:
Let's pretend A and B react to make C (can't get much simpler than that).
A + B --------> C
So we have a mixture containing A, B, and C. According to LeChatlier's principle, if we add more C to the mixture, the amounts of A and B will increase. If we remove some of the C from the mixture, A and B will decrease. And if we were to add A, B, or a combination of the two, C will increase. Still with me here? Good.
What's going on when we come off a cycle:
Ok, so while we're on the cycle, are natural test production is going down to compensate for the exogeneous test intake, and our production of other steroid hormones (i.e. Estrogen, Cortisol, etc.) is going up to compensate for the heightened test levels. When we come off a cycle, we cease intake of exogeneous testosterone. In other words, we have very low test levels, and very high cortisol and estrogen levels: it's the EXACT OPPOSITE of what we had while starting our cycle.
REMEMBER Le Chatelier's Principle because this is where it gets really important. When we have an excess of one hormone, the others will start shifting around, to attain a certain equilibrium. Ok, I'm gonna say it (and bold it) again because it's just that important. When we have an excess of one hormone, the others will start shifting around, to attain a certain equilibrium. It is a very common misconception that we want to eradicate estrogen :nono:. High estrogen levels play an integral part in Post Cycle therapy. That's right, you want to welcome high estrogen with open freaking arms, but there's a trick to it. And that trick is the almighty SERM (Selective Estrogen Receptor Modulator).
SERM's: the foundation of post cycle therapy:
Selective Estrogen Receptor Modulators are (and damn well should be) the foundation for any proper post-cycle therapy plan. A post cycle therapy plan without them, isn't a post cycle therapy plan: it's a bunch of crap you decided to take after doing a cycle. The purpose of a SERM is to block the negative effects estrogen, while your hormone levels go back to equilibrium.
SERM's are prescription drugs, and are NOT SOLD IN SUPPLEMENT STORES. In fact, there are only 3 ways ( can think of) in which you can obtain a SERM:
1) Through a Doctor's Prescription.
2) Through the Black Market (a.k.a. illegally)
3) As a research chemicals intended for use in lab rats.
The Different SERM's:
Tamoxifen (Nolvadex):
Reputation: Most popular SERM for post cycle therapy
Pros: Cheap. Effective for gyno prevention.
Cons: Heptatoxicity. Studies have shown it to lower IGF levels (I don't feel like citing, but it's about 20% decrease...IMO no biggie).
Popular Dosage (for a 4-week cycle): 40/40/20/20
Note: Tamoxifen Citrate is less potent, and should be dosed at an extra 30%.
Clomiphene Citrate (clomid):
Reputation: Second most popular. Usually taken the first week or so to speed up Testosterone recovery with Tamoxifen being taken the whole therapy.
Pros: Better than Tamoxifen for HTPA regernation. Less heptatoxicity. Does not lower IGF.
Cons: Less effective against gyno. Can cause emotional issues. May Cause blurred vision. Hot Flashes.
Popular Dosage (for a 4-week cycle): 100-200mg/100mg/50mg/50mg
Toremifene:
Reputation: Very popular on this board :think:
Pros: Much less toxic.
Con's: $$$$$expensive$$$$$
Popular Dosages (for a 4-week cycle): 120-240mg/120mg/60mg/30mg
Raloxifene:
Reputation: Very effective against gyno
Pros: Strong protection against gyno. Less toxic than Tamoxifen.
Con's: Cost Restricting. Can cause abnormal blood clotting in the eyes, lunges, and legs. May also cause hot flashes trouble breathing, and blurred vision.
Popular Dosages: (for a 4-week cycle): 120-240mg/120mg/60mg/30mg
Moving down the PCT Hierarchy: Cortisol Control
Excess cortisol can be damaging to your newly found muscle mass. Because of this, it is a good idea to use something to block or lower the excessive cortisol levels. Always start high, and taper your way down. Here's what we have to work with:
B-Androstenetriol (b-triol): This is one of the better cortisol suppressors. It has a terrible oral bioavailability, and should be taken transdermally. Dosages range from 25-50mg every 12 hours.
Methyl B-Androstenetriol (mb-triol): This is an enhanced version of b-triol designed for oral use. Because it is not an androgenic steroid, there is minimal heptatoxicity associated with it's alkylation. Found in the following products: Retain (by Anabolic Xtreme), Restore (by ALRI), Thyrogen-X (by ALRI)
7-Hydroxy-DHEA: Another potent cortisol suppressor with great oral bioavailability. Found in the following products: Lean Xtreme (by Designer Supplements), Reduce XT (by SNS)
7-oxo-DHEA (7-keto-DHEA): Still a decent contender, this has a terrible oral availability and an even worse half life (2 hours). This is best taken transdermally, where such effects can by bypassed.
Cissus: Unlike the above, the components of Cissus do not suppress Cortisol, but rather block cortisol receptors (better than Nandrolone or Dianabol according to some studies). Dosages vary significantly (pending extracts). SuperCissus by USPLabs is a high quality Cissus product.
Branched Chain Amino Acids: These should be a staple to begin with, but are a great anti-catabolic that mitigates the muscle-wasting effects of cortisol.
At the bottom of the PCT hierarchy there's AI's, Test Booster's, and other 'natural' anabolics
Way too many different things going on in here to go into too much detail. Just a word of caution (and this is my personal opinion), but if you're post cycle plan starts to look like a constitutional ammendment: you're over-doing it. And the worst part is if something goes wrong, you won't have a damn clue what caused it.
Honorable mentions of this part of the hierarchy:
Jungle Warfare (by ALRI)
MassFX (by Anabolic Xtreme)
Hyperdrol (by Anabolic Xtreme)
Ecdysterone/Turkesterone
Creatine Monohydrate
Can you tell I was bored after work today?
:smite: thesinner
Disclaimer: This post is for entertainment purposes only. I don't use or condone the usage of illegally obtained chemicals.
Author's Note: I cannot and will not give out any information on obtaining any of the drugs mentioned in this article. If you send me a private message asking for sources, I will reply with the following link everytime: Google
I would suggest buying nothing, and selling off your whatever steroids you were about to cycle........but that's just me (and about 95% of the other steroid users on this board).i appreciate what youre doing here, great stuff! But i'm planningt a post cycle therapy with only stuff that i could find at my supplement store. What would you suggest i buy when i walk into a Vitamin Store?
thats great advice! But i think ill try my luck...Last time i gained 15 lbs and was able to maintain. Call me old school..I would suggest buying nothing, and selling off your whatever steroids you were about to cycle........but that's just me (and about 95% of the other steroid users on this board).
Best of luck to you, but I'm speaking from experience when I say you'll soon wise up to these concepts if you continue 'risking it'. BTW, taking 'PCT Supplements' isn't old school in the least since, SERM's have been around and utilized much longer than most of these supplements people are taking for PCT.thats great advice! But i think ill try my luck...Last time i gained 15 lbs and was able to maintain. Call me old school..
Do you know anything close to SERM, that i can get at a store?Best of luck to you, but I'm speaking from experience when I say you'll soon wise up to these concepts if you continue 'risking it'. BTW, taking 'post cycle therapy Supplements' isn't old school in the least since, SERM's have been around and utilized much longer than most of these supplements people are taking for PCT.
You're trying to cut corners on the protocol I described. How can I help you when you refuse to adhere to the very basis of mt protocol? That's like asking me how to get in shape without working out or eating right......I'm sorry, but I don't have an answer for you.Do you know anything close to SERM, that i can get at a store?
I think I've made it pretty clear how to legally obtain the materials which you require, and to avoid doing so is nothing more than cutting corners on this protocol. :thumbsup:SERM's: the foundation of post cycle therapy:
Selective Estrogen Receptor Modulators are (and damn well should be) the foundation for any proper post-cycle therapy plan. A post cycle therapy plan without them, isn't a post cycle therapy plan: it's a bunch of crap you decided to take after doing a cycle. The purpose of a SERM is to block the negative effects estrogen, while your hormone levels go back to equilibrium.
SERM's are prescription drugs, and are NOT SOLD IN SUPPLEMENT STORES. In fact, there are only 3 ways ( can think of) in which you can obtain a SERM:
1) Through a Doctor's Prescription.
2) Through the Black Market (a.k.a. illegally)
3) As a research chemicals intended for use in lab rats.
youre gayYou're trying to cut corners on the protocol I described. How can I help you when you refuse to adhere to the very basis of mt protocol? That's like asking me how to get in shape without working out or eating right......I'm sorry, but I don't have an answer for you.
I think I've made it pretty clear how to legally obtain the materials which you require, and to avoid doing so is nothing more than cutting corners on this protocol. :thumbsup:
yes.youre gay
Don't taper down your dosages with an active steroid. Your body will be shutdown to the point that these lowered dosages will be pointless.OK, I am tracking with all of the products and what they do and why we need them when cycling on anabolics.
Now, my question would be, if I am going to begin a cycle of lets say Halodrol-50, would i begin any kind of therapy products during the cycle, or immediately following. also, would i take any liver protectant/cleanser products during, or after?
thank you, it would also help for some dosages and maybe a pyramid effect as well??
Ok, well i would just hate to not pct on some H-50 and turn around and get some gyno after my cycle. that would effing suckDon't taper down your dosages with an active steroid. Your body will be shutdown to the point that these lowered dosages will be pointless.
There's no need to take any post-cycle 'crap' while you're on an HD50 cycle. Sometimes AI's or SERM's are used while on a Test cycle, but in the situation you've mentioned, such things are not needed and serve no benefit.
There's a lot of argument as to whether a liver protectant/cleanser should be taken during or after the cycle. Personally, I take them year round.
I hope I've successfully answered all your Q's,
thesinner
Yeah, post cycle flare-ups do suck. (What do you think motivated me to learn all this PCT info?)Ok, well i would just hate to not post cycle therapy on some H-50 and turn around and get some gyno after my cycle. that would effing suck
No, APCT is not a SERM.would you consider anabolic xtremes advanced post cycle therapy a SERM?
Google my friend. It's got all the answers. Re-read the section of my article about SERM's. They are quite easily and quite legally available on the internet.damn, thats right. my bad, it is damn near ****ing impossible to get a SERM legally. **** ****. well, i guess i will have to make due or figure out some kind of alternative
Selective Estrogen Receptor Modulators are (and damn well should be) the foundation for any proper post-cycle therapy plan. A post cycle therapy plan without them, isn't a post cycle therapy plan: it's a bunch of crap you decided to take after doing a cycle. The purpose of a SERM is to block the negative effects estrogen, while your hormone levels go back to equilibrium.
SERM's are prescription drugs, and are NOT SOLD IN SUPPLEMENT STORES. In fact, there are only 3 ways ( can think of) in which you can obtain a SERM:
1) Through a Doctor's Prescription.
2) Through the Black Market (a.k.a. illegally)
3) As a research chemicals intended for use in lab rats.
Well the whole idea behind a pulsing cycle is no PCT. You should probably check out this thread: http://anabolicminds.com/forum/steroids/62121-how-pulse-orals.htmlI'm going to be running a pulse cycle of Epidrol.
M/W/F, 10/20/30 first week then 40mg on the subsequent doses.
Plan is for 8 weeks, will cut short to 6 if I start feeling suppressed.
Now at the end of the 8 weeks I'm planning on doing 3 weeks of Tamoxifen Citrate, 40mg first 7 days then 20mg the remaining two weeks. Also going to take X-Lean and PowerFULL.
What do you guys think? Would this be enough, it's a watered down post cycle therapy to be sure, but many are recommending no Tamoxifen at all... which... I'd rather be safe then sorry.
Also, what do you think of replacing the PowerFULL with JW? I'm a little leery about the claims that JW would suppress me and thus make this more like a 12 week cycle with no post cycle therapy instead of a 8 week. Thanks.
Hehe that's how I got turned on to the whole Pulse cycle idea in the first place, I've skimmed most of that monster thread, but yeah... just seems a lot of people are uncomfortable with taking steroids w/o a PCT, especially a SERM.Well the whole idea behind a pulsing cycle is no post cycle therapy. You should probably check out this thread: http://anabolicminds.com/forum/steroids/62121-how-pulse-orals.html
Pulse cycles are something a little different and don't quite follow the protocol being addressed here. Personally, I'm a bit skeptical of the pulse method on account of the lack of data behind it, but some people freakin' swear by it. Definitely check out the previously mentioned thread, that should give you the low down on whatcha need.
If you didn't really need it, then no benefit really. But what if you do need it? You see what I'm getting at? It's more of a security blanket. I would recommend you at least have some on hand just in case something bad happens. Tamox and Ralox can stop and prevent gyno if taken right when you notice them beginning to flare up.I guess would there be any negative side effects of taking Tamaxofin if I didn't really need it?
Thanks for your help! Yeah I wanted to take the SERM just to stave off any side effects, but if they're very fast acting I'll just keep it on hand incase I notice gyno.If you didn't really need it, then no benefit really. But what if you do need it? You see what I'm getting at? It's more of a security blanket. I would recommend you at least have some on hand just in case something bad happens. Tamox and Ralox can stop and prevent gyno if taken right when you notice them beginning to flare up.
That still makes me wonder since Clomid is actually better at restoring HPTA. To me this is more important in pct than "possibly" preventing gyno. Wouldn't a clomid only pct be better since shutdown is basically a given with an exogenous source of test. Then just have some Nolva on hand in case of gyno issues?People typically don't use clomid because 1) Nolvadex is cheaper. 2) Nolvadex puts up a better fight against gyno. 3) Clomid can make you emotional and depressed.
There's not enough data out there to be able to make a 'for sure' suggestion as to the effectiveness of these.IAlthogh it wasnt mentioned above, to stimulate LH while on cycle, does anyone have any input as to whether herbs like trib or fen or longjack would be beneficial while ON for this purpose and this purpose only?
There's not enough data out there to be able to make a 'for sure' suggestion as to the effectiveness of these.
In my opinion, proactive on-cycle test stimulation is not going to be of much effect because the amount of exogeneous test/steroids will far too greatly outnumber whatever you are taking to combat against downregulation. Also note that a lot of these steroids have a higher anabolic ratio that testosterone. So what would be the benefit of increasing endogeneous testosterone if it is only going to be competing with the the steroids you are using for androgenic receptors?
Some people like the idea. Then again, some people like Muscletech Products. I can't tell you which path to take, but I can at least show you the one I walk, and why I walk it.
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